I first saw 'The Silence of the Lambs' as a teenager and was absolutely fascinated by Hannibal Lecter. He's just one of those characters. It's that mix of extreme intelligence and a strange kind of physicality that Anthony Hopkins brings to the part that makes it so memorable, every scene he's in glues you to the screen.
This drawing's from the moment when he finally escapes from his cell. It's a significant scene for a number of reasons, not the least of which is because up until this point we've only been told about how dangerous Lecter is, but all of a sudden he's out of his cage and you get to see what he's capable of. It's a scene that stays with you.